বৃহস্পতিবার, ১৪ মার্চ, ২০১৩

Mozilla launches Open Badges 1.0, delivers virtual kudos for real skills

Mozilla launches Open Badges 10, delivers virtual recognition for real skills

We've long missed the stickers and badges we could wear to show achievements in our childhood, whether it was an A+ in History or our campfire-making chops. Mozilla must miss those too, as it's launching Open Badges 1.0, a spec for proving skills on the web. The approach provides verifiable credentials that are stowed away in a virtual Mozilla backpack and shareable through a number of online avenues, starting with WordPress blogs and Twitter updates. You won't necessarily need to be a web scripting wizard to earn badges, either -- they're available or coming from 600-plus companies and educational institutions that include Disney-Pixar, NASA and the Smithsonian. We're a long way from only having to flash our Open Badges to land a job, but those symbols may be enough to let teachers and coworkers know we're up to snuff for key tasks.

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Source: Mozilla Open Badges

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/AHiSZoXTkZg/

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Kindle Fire HD 8.9 launched in Europe and Japan, gets permanent price cut in the USA

Kindle Fire HD 8.9 launched in Europe and Japan, gets permanent price cut in the USA

Amazon today launched its largest slate, the Kindle Fire HD 8.9, in Europe (the UK, Germany, France, Italy and Spain, to be exact) and Japan, where it's been up for pre-order since late last month. That's not all, though, as Amazon says having to make more 8.9-inch tabs for those markets has cut production costs, and the savings are being passed on to US customers in the form of a price cut. This isn't one of the time-sensitive offers Amazon has a habit of pulling, so from today onwards, you'll be able to pick up a WiFi-only 16GB model for $269, or the 4G option with 32 gigs of storage for $399. The higher capacity models -- 32GB WiFi-only and 64GB with 4G -- now tally up at $299 and $499, respectively.

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Source: Amazon

Source: http://www.engadget.com/2013/03/13/kindle-fire-hd-8.9-launch-europe-japan-us-price-cut/

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বুধবার, ১৩ মার্চ, ২০১৩

Arrested Development's Mitch Hurwitz And Will Arnett On Taking Their Show To Netflix

arrested devOne of the big events coming up for comedy fans this spring will be the return of Arrested Development, which will debut its fourth season on Netflix after a long hiatus. Creator Mitch Hurwitz and star Will Arnett took a few minutes out of their busy lives to answer a few questions about the show. So what's it like being a big star on TV and then going to the Internet instead?

Source: http://feedproxy.google.com/~r/Techcrunch/~3/AFUqJrpnFE4/

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PFT: Lions want Bush signed before he leaves town

Percy HarvinAP

During his first few years with the Minnesota Vikings, Percy Harvin had been plagued by migraines that affected his ability to perform in practice and even games.

Harvin missed three games and countless practices in Minnesota as migraines would appear and render Harvin completely incapable of performing. However, Harvin believes those struggles are officially in the past.

?I haven?t had a migraine in two years now,? Harvin said. ?Been fully healthy from that aspect so everything?s been good. I?m going to knock on wood that nothing resurfaces but it?s been all great.?

Harvin was diagnosed with sleep apnea after an episode where he collapsed at practice during training camp in 2010. Harvin thanked Vikings owner Zygi Wilf and the Wilf family for sending him to the Mayo Clinic to be evaluated and to take care of him during his medical issues. With the diagnosis in place and knowing how to treat it, Harvin hasn?t had a migraine since.

The news has to be music to the ears of the Seattle Seahawks front office in knowing that their offensive weapon won?t be missing any time with them because of the ailment.

Source: http://profootballtalk.nbcsports.com/2013/03/12/lions-want-to-get-bush-signed-before-he-leaves-town/related/

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Ultisky.com Reveals The Best Way To Make Money For Internet ...

Ultisky.com announced the best way to make money for Internet Entrepreneurs today. Providing a lifestyle testimony for what it takes to succeed online and how others can achieve the same level of success. Revealing how Peng Joon's the Work From No Home System was a major boost for their business models.

http://ultisky.com/best-way-tomake-money-work-from-no-home-system-lifestyle-testimony/

According to Kyle Ransom, founder of Ultisky.com the reason he created a special lifestyle testimony page was because he feels very lucky everyday. Ransom says that he enjoys not running a traditional business and the comforts of not having to punch a time clock. He feels most people have to drag themselves to work every single day and do a job that they hate.

Ransom credits Peng Joon and the Work From No Home System as a great enhancement tool that can help grow business models. He stresses every business must learn how to compete online as well as in the mobile market. Citing that the Work From No Home System is ideal to assist serial Internet Entrepreneurs who have sold hundreds of online products to newbies starting from scratch.

?It's very important that any Internet Entrepreneur learn to conduct their own due diligence to decide if a system or method will add value to their business model,? stated Kyle Ransom.

Continuing Ransom expresses that the secret formula to make money online in a bad economy is having the right information. Urging that most people don't put themselves in the position to be at the right place and at the right time. Challenging that if more people learned the secrets of how to apply varies methods in their business models they can achieve a higher level of success.

On the Ultisky.com website visitors may sign up for a V.I.P email list to learn valuable information about the best ways to make money online.

http://ultisky.us1.list-manage1.com/subscribe?u=b1c3ece940aef17ee288cbcef&id=ab07f0dc0c

For more information please contact Ultisky.com directly via their website at http://ultisky.com .

Source: http://ultiskyinc.pressdoc.com/41055-ultisky-com-reveals-the-best-way-to-make-money-for-internet-entrepreneurs

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Grieving husband pushes bill for unproven remedies

(AP) ? After the best-selling Irish novelist Josephine Hart died from ovarian cancer in 2011, her husband was so devastated he often went to her grave to have breakfast.

And even now, Lord Maurice Saatchi describes his wife's cancer treatment as "medieval." A member of Parliament, he's proposing a bill that would allow doctors to use experimental therapies even if there is no proof they work.

Hart and Saatchi were an oft-photographed celebrity couple in Britain more than a decade ago. She produced plays in London's West End and hosted poetry readings featuring actors including Ralph Fiennes and Roger Moore. Her 1991 novel "Damage" was turned into a film starring Jeremy Irons and Juliette Binoche.

Saatchi, an advertising executive who sits in the House of Lords, acknowledges his bill was driven by grief at his wife's death.

After a diagnosis in 2009 that her cancer was too advanced for surgery, Hart got chemotherapy and radiation, which Saatchi calls "degrading and ineffective."

Though ovarian cancer is one of the hardest to catch and treat early, Saatchi says Britain's current law is a serious barrier to new treatments. Theoretically doctors can be prosecuted if they try something that deviates from standard practice.

His bill is aimed at encouraging new therapies by allowing doctors to try them, including those lacking evidence of effectiveness. The decision would have to be made by several medical experts in different fields and doctors would need to tell their supervisors in advance as well as inform the patient of any opposing medical opinions.

While bills initiated by individual politicians rarely make it into law, Saatchi's proposal has raised a broader issue about British health care: Survival rates for most cancers are worse than in other European countries including France, Germany and the United States. A report released this month said Britain ranked 16th out of 19 Western countries for ovarian cancer death rates.

Access to drugs is so poor the government started a 200 million pound (US$302 million) emergency fund in 2010 to try to get patients quicker treatment; the U.K. spends about half what France spends on cancer drugs.

According to the Organization for Economic Co-operation and Development, the five-year survival rate for breast cancer in the U.S. is 89 percent. In the U.K., it is 81 percent.

After the cancer drug Avastin was approved for use in the U.S., it took nearly another year for it to become available in Britain. For Tykerb, the delay was more than two years. Avastin is used to treat numerous cancers including those of the kidney, colon, and lung while Tykerb is used to treat breast cancer in combination with other drugs.

In a debate on Saatchi's bill in the House of Lords in January, Lord Frederick Howe, a government health minister, lamented the contrast between Britain's role as a world leader in health research and its lagging approval of new treatments for patients.

"It still takes an estimated average of 17 years for only 14 percent of new scientific discoveries to enter day-to-day clinical practice," he said. "This is not acceptable."

Several other members voiced support for Saatchi, citing other problems that have slowed medical advances, including bureaucracy and slashed budgets.

Some experts suggest that if Saatchi's bill doesn't make it into law in its current form, its key planks might be rolled into a government-sponsored bill, making it much likelier to succeed. Saatchi has even been advised by the U.K.'s top medical officer."We're very sympathetic to the points that Lord Saatchi has raised," said Daniel Poulter, a minister in the Department of Health, during a televised discussion with Saatchi. "We'd certainly like to engage further."

Legal experts said current British law should be sufficient to protect doctors who try experimental procedures as long as there is some reason to think they might work and the patient agrees. But a High Court judge ruled in 1957 that doctors could be found negligent if they used treatments that strayed from common practice, setting a precedent often cited in medical negligence lawsuits. In that case, the judge ruled that doctors must act in accordance with what the majority of doctors do, even if there are opposing medical views.

According to National Health Service records, the number of medical negligence suits has jumped by about 30 percent since 2010. Though it is rare for doctors to be penalized for using new treatments, experts said many doctors are wary.

"Doctors are very fearful that if they do anything innovative, the lawyers will get them," said Charles Foster, who teaches medical law and ethics at Oxford University. "There's a culture of following guidelines where they think they will only be safe if they treat patients conservatively," he explained.

Foster said Saatchi's bill could be important in addressing doctors' misconceptions of what the law allows. "It could change the zeitgeist of the medical profession and make them more willing to try new things," he said.

Still, some aren't convinced Saatchi's bill would help speed new treatments. Dr. Karol Sikora, director of CancerPartners U.K., a network of treatment centers and dean of the medical school at the University of Buckingham, thinks the proposal is superfluous.

"If the doctor wants to do it and the patient consents, people can do wacky things," Sikora said, citing the alternative medicine industry, where there is little evidence treatments work. He also said the bill could encourage false hope among terminal patients.

Saatchi doesn't know whether his bill would have helped his wife. Ultimately, he said, it's about giving patients and doctors new opportunities in the future. "This bill is not going to cure cancer, but it will encourage the man or woman who will," he said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/bbd825583c8542898e6fa7d440b9febc/Article_2013-03-13-EU-MED-Britain-Cancer-Bill/id-e0327419e2c14de8959fc187a78ea190

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সোমবার, ১১ মার্চ, ২০১৩

Untreated Depression in Pregnant Women - Part 2 | Family Mental ...

Untreated Depression Pregnancy

This week I?m highlighting recent expert opinions on untreated depression during pregnancy. My post a few days ago highlighted a research paper stating that anti-depressants generally ?do not provide clinically meaningful benefit to women with depression.?

While a strongly disagree with that position, I am impressed by the number of non-medication therapies that are being researched or have already shown benefits for women with depression.

And now we get to ?the rest of the story?.

A letter of response was submitted in the same research journal not long after the first paper was published. The letter?s authors disagreed with the conclusions made in the paper, especially that anti-depressants were so ineffective for women. They stated that while research studies doing random medication trials with pregnant women are unethical, that didn?t mean there was no useful data.

According to these experts, the research paper?s authors may have had the wrong assumptions about pregnant women with mental health issues. Because of the complexities of depression in pregnant women, medication can be a critical part of their care.

More than anything else, the authors of this letter thought the researchers minimized the seriousness of depression during pregnancy. They feel that a research paper with these conclusions creates ?harmful hype? for a problem that is already challenging to address.

So why have I summarized two papers that seem to show such opposite view of the same problem? To show you that not all research is the same. It?s important to see how experts come to the conclusions they publicize in papers, articles, and interviews. Also, some issues are complex and the available information can be controversial or conflicting.

Consider that even though I didn?t agree with the some of the conclusions in the first research paper, I still found something valuable from it. The list of alternative therapies looks like a promising direction for future research.

There is much research to be done about depression during pregnancy. Hopefully, more questions will be answered and research results will become more consistent. Until then, be sure you get information from all sides of an issue to make your own conclusions.

Here?s a link to the letter of response again.

Erika Krull, MS, LMHP is a practicing licensed mental health counselor in Nebraska. Visit her site marriageincrisistoday.com to learn more about saving a troubled marriage.

Like this author?
Catch up on other posts by Erika Krull, MS, LMHP (or subscribe to their feed).



????Last reviewed: 10 Mar 2013

APA Reference
Krull, E. (2013). Untreated Depression During Pregnancy ? Part 2. Psych Central. Retrieved on March 11, 2013, from http://blogs.psychcentral.com/family/2013/03/untreated-depression-during-pregnancy-part-2/

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Source: http://blogs.psychcentral.com/family/2013/03/untreated-depression-during-pregnancy-part-2/

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রবিবার, ১০ মার্চ, ২০১৩

Venezuela's Capriles says "evaluating" election date ruling

KRANJSKA GORA, Slovenia, March 10 (Reuters) - Ivica Kostelic used all his experience to win the men's World Cup slalom race in Kranjska Gora on Sunday, 10 years after his first victory in the Slovenian resort. Hampered by a lingering knee injury, the Croatian had not won a slalom race this season but the 33-year-old broke his duck in style to earn his 26th World Cup victory after clear first-leg leader Alexis Pinturault messed up his second run. The 33-year-old clocked a combined time of one minute 45. ...

Source: http://news.yahoo.com/venezuelas-capriles-says-evaluating-election-date-ruling-222411422.html

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We're live at SXSW's Virtual Reality: The Holy Grail of Gaming panel with Oculus and more

We're live at SXSW's Virtual Reality The Holy Grail of Gaming panel with Oculus and more

What? You didn't think we'd make it out of the first day of SXSW without some gaming coverage, did you? We're here at the show's Gaming Expo, a room full of the latest and greatest offerings from companies big and small. We couldn't help but do a doubletake when we saw the lineup for the rather verbose Virtual Reality: The Holy Grail of Gaming. The panel's got Cliff Bleszinski (Epic), Palmer Luckey (Oculus Rift), and Chris Roberts (Wing Commander) -- an impressive offering moderated by Oculus' Nate Mitchell. Strap on those goggles and come talk VR with us after the jump.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/ARD1NQIlK7A/

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বৃহস্পতিবার, ৭ মার্চ, ২০১৩

DOJ lets waiting period expire on T-Mobile / MetroPCS merger, hints it's good to go

MetroPCS street ad

We're sure that MetroPCS and T-Mobile USA executives were on pins and needles wondering whether or not their proposed merger would clear all the regulatory hurdles. While they're not officially free and clear, the Department of Justice has given a strong hint that the carrier union will go through. The government branch just let the mandatory waiting period expire without raising any objections; if it had thought there were serious antitrust issues, it would have piped up by now. Before anyone pops the champagne corks, though, there's still a number of formalities -- the Committee on Foreign Investment, the FCC and the companies' shareholders still need to sign off on the deal, which could take weeks or longer. Considering the troubles T-Mobile had the last time it tried a merger, though, waiting will seem like a walk in the park.

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Source: CNET

Source: http://www.engadget.com/2013/03/06/doj-lets-waiting-period-expire-on-t-mobile-metropcs-merger/

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Bill to avert government shutdown fast tracked in the House

House Majority Leader Eric Cantor and Speaker John Boehner. (The Washington Post/Getty Images)

With a nasty weather system threatening the nation's capital, the House on Wednesday will fast-track a bill to keep the government funded through the current fiscal year. It will incorporate the lower funding amounts mandated by sequestration.

The vote on the bill, known as a "continuing resolution," begins the process of avoiding a government shutdown, which would occur on March 27 if lawmakers are unable to agree on spending rates.

While the House bill includes the $85 billion in cuts as part of sequestration, Republicans have moved to soften the blow to the Pentagon and the Department of Veterans Affairs by providing flexibility for those agencies on how to spread out the mandated spending reductions. The bill will also include funding for the Affordable Care Act, which will cause some consternation from the House's more conservative ranks, though likely not enough to tank the measure.

House Minority Whip Steny Hoyer, a Democrat of Maryland, said on Tuesday that he's not actively urging his party to oppose the spending bill, so it may receive some level of bipartisan support.

In lieu of traditional budget resolutions, the federal government, for most of the Obama administration, has been funded by short-term agreements that require regular votes to avert a shutdown. While in the past these votes required intense negotiation between the parties?lasting until the final hour of the shutdown deadline?the current extension is expected to pass through both chambers with relatively little controversy.

The vote in the House and the following vote in the Senate next week will give both chambers a full two weeks?an eternity in Washington?to work out any differences in their bills.

Senate Majority Leader Harry Reid, speaking with reporters after meeting with members of the Senate Democratic caucus on Tuesday, said he's "cautiously optimistic that we can reach a solution before we leave here before the Easter recess after we do the budget."

Later, when asked about possible divisions between the bill the Senate will vote on and the House version, the Nevada Democrat predicted that his chamber would also want to offer flexibility to other agencies on how to handle the sequester cuts. "We believe that this being a bicameral legislature, that we also have the right to have some appropriation bills and that we also have the right to have some anomalies," said Reid. "That's what we're going to be focusing on."

The bill's passage would come a full six months before the fiscal year ends, giving lawmakers time to continue work on a more substantive agreement on long-term government spending. Although negotiations for a "grand bargain" have stalled in the past, President Barack Obama this week began reaching out to lawmakers to reinvigorate talks.

The president plans to visit Senate Republicans at their weekly lunch meeting on Capitol Hill next Tuesday.

Source: http://news.yahoo.com/blogs/ticket/bill-avert-shutdown-fast-tracked-house-155342952--politics.html

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বুধবার, ৬ মার্চ, ২০১৩

Video: Housing: Then & Now

Sorry, Readability was unable to parse this page for content.

Source: http://www.nbcnews.com/video/cnbc/51052030/

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CONSUMER WATCH: Standard Insurance Doesn't Cover Fuel Leak ...

Posted on: 6:16 pm, March 4, 2013, by Dave Bohman, updated on: 08:11pm, March 4, 2013

UNION COUNTY ? A family in Union County wondered how they would pay for an expensive cleanup when their heating oil tank sprung a leak.

The family learned the hard way their homeowner`s insurance policy did not cover damages from a fuel tank leak, so they turned to Action 16 Investigative Reporter Dave Bohman for help.

Ronda Steen returned to her house outside Lewisburg Feb 15th. , to a sickening odor.

?The smell burned your eyes,? said Ronda.? ?It was just hard to breathe.?

She just had her heating oil tank filled.

?Three days after i filled it, it read `Empty,`? she added.

She then learned her tank sprung a leak.

An environmental cleanup company found about 200 gallons of home heating oil from the leaky tank seeped into the soil and into the basement walls.

The Steen home is insured by Allstate which arranged to clean up and remove contaminated dirt.

But the company also told Ronda, her policy doesn`t cover the cleanup costs and she?d have to pay for it.

?What is the sense of paying money to an insurance company, if you have no coverage, but for maybe a fire?,? Ronda asked.

Ronda Steen?s friends at a local church saved the family from a homeless shelter, arranging for the family to stay in a dorm room at a nearby college.

But the situation had the Steen?s nervous, as they live on a $1,200 a month disability check.

?I`ll be honest, it sent me to tears, and talking about it, it still does,?

We called Allstate.

A spokesman confirmed standard homeowner`s insurance does not cover fuel tank leaks but he added Allstate?s Board of Directors authorized the Steens to be a hardship case, and the company will pay for the cleanup.

The Steen`s hope to be able to move back in later this month, and hope people with older heating oil tanks either check their tanks, or their insurance policies.

The Insurance Information Institute tells us most homeowner policies only cover fuel spills if the company inspects the heating oil tank before writing a policy.

Unless the home is new, it means most homeowners will have to either buy a new tank, or buy extra insurance, otherwise, they?ll be forced to pay for a very expensive cleanup out of pocket if their tank springs a leak.

Source: http://wnep.com/2013/03/04/consumer-watch-insurance-does-not-always-cover-damage-from-leaky-fuel-tanks/

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মঙ্গলবার, ৫ মার্চ, ২০১৩

Niles Animal Hospital and Bird Medical Center: Pet Toxins in Your ...

From the AVMA Pet SmartBrief.....



We think that our indoor pets are safe from predators, cars and
disease, but our homes may be exposing our pets ? and ourselves ? to
risks of a different realm.

Everything from the mattresses we sleep on to the motes of dust on the shelves may contain flame retardants or other chemicals, says Laurel Standley, an environmental consultant and author of ?#ToxinsTweet: 140 Easy Tips to Reduce Your Family?s Exposure to Environmental Toxins.?

Standley began studying the effects of household toxins in pets after she, her mother and sister all lost pet cats to cancer.

She grieved the losses but Standley, who earned a doctoral degree in chemical oceanography, also grew concerned about what made them sick in the first place.

She worries about the prevalence of chemical flame retardants known as polybrominated diphenyl ethers (PBDEs) found in many electronics, polyurethane foams, carpet padding, furniture, mattresses and other common household items.

?Each time we sit down on couches with foam cushions, dust particles fly out and fill our homes with dust containing flame retardant chemicals,? Standley says.

The products are being phased out after growing concern about their health effects. Last month, California Gov. Jerry Brown proposed new standards to reduce use of fire-retardant chemicals in furniture and baby products.

Some studies have associated hyperthyroidism in cats to the presence of PBDEs, including one published in February 2012 in the Journal of Toxicology and Environmental Health.

?Proving cause and effect is extremely difficult,? Standley says, ?But that?s not an excuse to not protect our pets.?

Plastics also contain harmful chemicals, including bisphenol A and phthalates that have been associated with reproductive and other endocrine effects.

Some of these chemicals have been restricted from children?s products (such as the Multnomah County ban on sippy cups and baby bottles made with BPA).

?The same chemicals haven?t been regulated for dog or cat toys,? says Jennifer Coleman, outreach director at Oregon Environmental Council. ?They could still have an impact on endocrine systems.?

Like infants, pets are also smaller than adults, metabolize more quickly and are closer to the ground. This makes them more vulnerable to harm from many of the products humans use, she says.

One way to reduce their exposure is by replacing plastic food bowls with those made from stainless steel, ceramic or glass instead, Standley suggests.

The fish in those food dishes can also be toxic; fish living in polluted streams can accumulate toxic substances in their systems, she says.

Even the plastic liner of the cans they come in may leach BPA.

Pigments and dyes are also likely to contain chemicals, so look for toys without a lot of color or bleaching, Coleman advises.

?My strategy with my own dog is to do the simple things that make the most sense to me,? she says.
She avoids vinyl and PVC plastic and opts instead for those made from rubber or fabric, such as tug ropes and stuffing-free toys. Even tennis balls can be toxic; the ones designed for dogs often contain lead.

Of course, some toxins will make your pet sick sooner rather than later.

At DoveLewis, veterinarians see some toxins more often than others. Metaldehyde slug bait ingestion can cause major muscle tremors that can be fatal, as well as liver problems, says staff veterinarian Dr. MeiMei Welker.

The emergency animal hospital also sees a fair number of dogs sick from marijuana ingestion, while rodenticide toxicity - suspected in the death of a prize-winning Samoyed recently- is a near-daily occurrence.
There are several kinds of rat bait, but the anticoagulant rodenticides are slower to act and allow more of a window of time to administer the antidote.

If your pet consumes poison of some sort, it?s best to bring the packaging to the veterinarian so he or she can treat it most effectively.

Other common toxins seen at DoveLewis include raisins and grapes; the sugar substitute Xylitol; Easter lilies; chocolate; ibuprofen and naproxen (Aleve); and acetaminophen.

The canary in the kitchen
Birds are uniquely sensitive to their environment; there?s a reason the phrase ?canary in a coal mine? became so popular.

They?re very sensitive to aerosols, and their respiratory systems are very different than ours, says Dr. Marli Lintner of the Avian Medical Center.

Bird lungs are designed to breathe in very clean, thin air, so breathing in some toxic inhalants can kill them immediately or make them very sick.

?Any sort of fume that makes your nose tingle or your eyes water is bad news for the birds,? Lintner says.
Fumes from nonstick pans pose one of the biggest threats to our feathered friends.

Once the pans overheat ? usually when the temperature reaches above 530 degrees Farenheit - a gas called polytetrafluoroethylene is released, says Dr. Deborah Sheaffer, staff veterinarian at the Audubon Society of Portland.

They can die very quickly, so if you see your bird panting or having trouble breathing, you should take it to the veterinarian immediately.

Lead poses another common avian household hazard. Paint, stained glass window frames, curtain weights, costume jewelry; foil from champagne bottles; and old bird cages can all be toxic.

?When people have pet birds, they really need to be cognizant of what?s around them,? Sheaffer says. ?They?re curious and inquisitive and they like to chew on things.?

This may be a lot of information for you to chew on too. Just remember that making your home safer for your pets makes it safer for humans as well.

Offering your pet toys made from fabric or natural rubber instead of vinyl and PVC plastic can help reduce their exposure to harmful chemicals.
??
How to help reduce toxins in your home

  • Vacuum frequently, preferably with a cleaner fitted with a HEPA filter, even on tile or wood floors (the goal is to not sweep dust up from the floor).
  • Eliminate carpet wherever possible; the less carpet you have, the easier it is to control dust.
  • Use rugs made of natural fabrics, such as cotton, wool or jute.
  • Vacuum your couch regularly.
  • Dust with a simple damp rag. Dry dusting can stir dust back into the air.
  • Replace plastic food dishes with those made from stainless steel, ceramic or glass instead.
  • If you have birds, avoid using nonstick pans whenever possible.
  • Don?t expose birds to smoke or household aerosol products such as harsh cleaners, perfumes, hairspray, etc.
  • Keep pets off the countertops and secure medications and other toxins safely in cupboards.
  • If you?re afraid your pet ingested something he shouldn?t have, call the Pet Poison Helpline at 800-213-6680 (consultations cost $39).
  • Don?t try to make your pet vomit; in some cases it could make the situation worse.

Source: http://blog.nilesanimalhospital.com/2013/03/pet-toxins-in-your-home.html

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সোমবার, ৪ মার্চ, ২০১৩

Vortex loops could untie knotty physics problems

Mar. 4, 2013 ? University of Chicago physicists have succeeding in creating a vortex knot -- a feat akin to tying a smoke ring into a knot. Linked and knotted vortex loops have existed in theory for more than a century, but creating them in the laboratory had previously eluded scientists.

Vortex knots should, in principle, be persistent, stable phenomena. "The unexpected thing is that they're not," said Dustin Kleckner, a postdoctoral scientist at UChicago's James Franck Institute. "They seem to break up in a particular way. They stretch themselves, which is a weird behavior."

This behavior culminates in what the UChicago researchers call "reconnection events." In these events, the loops elongate, begin to circulate in opposite directions, move toward each other and collide (the reconnection). Parts of the vortices then annihilate other parts, changing their configuration from linked or knotted into one that is unlinked or unknotted.

Kleckner and William Irvine, assistant professor in physics, report their findings on the creation and dynamics of vortex rings in Nature Physics, published online on March 3. Their work relates to deep questions in a variety of physics subfields, including turbulence, plasma physics, ordinary fluids and the more exotic superfluids. Knotted structures are thought to occur in all these phenomena but are difficult or impossible to observe.

"We look at plasma physics and turbulence every day in the sun," Irvine said, yet such phenomena pose longstanding, unsolved scientific puzzles. But knots may offer a means of untangling the complicated behavior of the electrically charged gas in plasma flows, for example, and for understanding the energy transport of complex flows in regular fluids and superfluids.

Conservation of quantities like energy and momentum are among the most important principles in physics. In many systems, the degree of "knottedness" can be represented as a precise physical quantity that also is conjectured to be conserved. "If confirmed, this would deepen our understanding of the dynamics and connections between many disparate physical fields," Irvine said. "We don't know if its true or not, but I think we can finally test this in experiment. There's actually around 50 years of theory on this subject with no clean experiments."

Colliding smoke rings

Irvine became interested in knot physics as a postdoctoral scientist at New York University after watching a smoke-ring demonstration in Washington Square Park. He wondered if he could get colliding smoke rings to become tangled. After unsuccessfully trying to make them himself he learned that others had tried before and failed.

"At some point the enthusiasm wanes and you worry about whether there's a very good reason why nobody has ever done this," Irvine said. "But sometimes going into a new field with a little naivete can be helpful."

Seeing a video of dolphins blowing air-core vortex rings convinced Irvine of the feasibility of the feat. He tried again, with Kleckner's assistance, soon upon arrival at Chicago. "Before we built the lab we had this little prep room, and we started with a little water tank," Irvine said. They tried to generate rings that would collide and then connect with each other, but the effort "failed catastrophically," Irvine said.

The duo overcame their experimental difficulties by designing and fabricating various hydrofoils (wings used in water) on a 3-D printer. They tried approximately 30 different shapes before they successfully created the desired vortices. When accelerated in a water tank at more than 100 g, hydrofoils leave behind bubble-traced vortex loops, whose dynamics the researchers recorded with a high-speed camera.

"The bubbles are a great trick because they allow you to see the core of the vortex very clearly," Irvine said.

The collaborative intellectual spirit and shared resources of the James Franck Institute also proved critical. "We wouldn't have succeeded without this sort of atmosphere," he said.

Lord Kelvin's knots

The roots of Irvine's work date back to the days of Lord Kelvin, more than a century ago. Kelvin had seen a demonstration of a vortex ring by physicist Peter Tait, and was fascinated by their elegance and stability.

"This was at the time when nobody knew what atoms were and the aether was still in fashion," Irvine said. In Kelvin's day, physicists theorized that the universe was filled with a substance known as aether, which transmitted light waves across the vacuum of space much like air transmits sound through the atmosphere. Kelvin thus proposed that atoms were vortex rings and knots in the aether, where the different types of knots formed the building blocks for the periodic table of elements.

The idea that atoms were simply knots tied in the aether eventually failed. But it failed in such an interesting way, Irvine said, that it gave birth to the fruitful study of knotted systems in mathematics and physics.

In future research, Irvine and Kleckner hope to perform some of their experiments at larger scale to investigate whether size would lend greater stability to vortex rings. They also are investigating the fine scale features of the vortices and whether "knottedness" is, or can be, conserved in fine-scale twisting of the vortex loops. "This is not something we presently know," Kleckner said.

Funding: A.P. Sloan Foundation, Packard Foundation and National Science Foundation.

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The above story is reprinted from materials provided by University of Chicago. The original article was written by Steve Koppes.

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/3ga896MiKyQ/130304130802.htm

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Adding to the list of disease-causing proteins in brain disorders

Mar. 3, 2013 ? A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders. James Shorter, Ph.D., assistant professor of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania, Paul Taylor, M.D., PhD, St. Jude Children's Research Hospital, and colleagues describe in an advanced online publication of Nature that mutations in prion-like segments of two RNA-binding proteins are associated with a rare inherited degeneration disorder affecting muscle, brain, motor neurons and bone (called multisystem proteinopathy) and one case of the familial form of amyotrophic lateral sclerosis (ALS).

"This study uses a variety of scientific approaches to provide powerful evidence that unregulated polymerization of proteins involved in RNA metabolism may contribute to ALS and related diseases," said Amelie Gubitz, Ph.D., a program director at the National Institute of Neurological Disorders and Stroke (NINDS).

ALS, or Lou Gehrig's disease, is a universally fatal neurodegenerative disease. Previous studies found that mutations in two related RNA-binding proteins, TDP-43 and FUS, cause some forms of ALS, but more proteins were suspected of causing other forms of the disease. TDP-43 and FUS regulate how the genetic code is translated for the assembly of proteins.

There are over 200 human RNA-binding proteins, including FUS and TDP-43, raising the possibility that additional RNA-binding proteins might contribute to ALS pathology. Computer algorithms, based on protein sequences, designed to identify yeast prions predict that around 250 human proteins, including several RNA-binding proteins associated with neurodegenerative disease, harbor a distinctive prion-like segment. These segments are essential for the assembly of certain protein complexes. But, the interplay between human prion-like segments and disease is not well understood.

Using yeast as a model organism, co-author Aaron Gitler, while at Penn in 2011, surveyed 133 of 200-plus candidate human RNA-binding proteins to predict new ALS disease genes, other than TDP-43 and FUS. They further winnowed the candidates to about 10 proteins with prion-like segments, and selected two candidates, TAF15 and EWSR1, for further study. Both TAF15 and EWSR1 aggregated in the test tube and were toxic in yeast.

Remarkably, they also uncovered TAF15 and EWSR1 mutations in ALS patients that were not found in healthy individuals. Based on these findings, they proposed that RNA-binding proteins with prion-like segments might contribute very broadly to the pathology of ALS and related brain disorders.

Characterizing the Top-Ten

Taylor, Gitler, Shorter, and others continued to characterize the top-ten human RNA-binding proteins with prion-like segments. The Nature study describes that two more of the top-ten candidates, called hnRNPA1 and hnRNPA2B1, are mutated and cause familial cases of brain disease. The mutations in hnRNPA1 and hnRNPA2B1 were present in two families with an extremely rare inherited degeneration affecting muscle, brain, motor neuron, and bone and another from a person with familial ALS.

Mutations in these two proteins fell in the prion-like segments and coincided with "sticky" regions in the proteins, making these regions more prone to assemble into self-organizing fibrils. The normal form of the proteins shows a natural tendency to assemble into fibrils, which is exacerbated by the disease mutations.

"The mutations accelerate the formation of the fibrils that recruit normal protein to form more fibrils," noted co-first author Emily Scarborough, from Penn. This dysregulated assembly likely contributes to disease. Indeed, the disease mutations also promote excess incorporation of the proteins into stress granules within a cell and the formation of clumps in the cells of animal models of human neurodegenerative disease.

"Neurodegenerative disease could ensue from unregulated fibril formation initiated spontaneously by environmental stress or another factor that regulates a protein's assembly," says Scarborough.

"This paper reflects an amazing collaborative effort and provides a great example of how understanding the underlying pure protein biochemistry can help explain how genetic mutations might cause pathology and disease," says Shorter.

"The findings confirm a strong prediction that the disease-causing mutations make the prion-like segment 'stickier' and more prone to clump," added co-first author Zamia Diaz, also from Penn.

Diseases associated with fibrils forming from prion-like domains in proteins frequently show "spreading" pathology, in which cellular degeneration via inclusions starts in one center of the brain and "spreads" to neighboring tissue. Although not directly addressed in the Nature study, the findings suggest that cell-to-cell transmission of a self-templating protein could contribute to the spreading pathology that is characteristic of these diseases.

"Related proteins with prion-like domains must be considered candidates for initiating and perhaps propagating similar pathologies in muscle, brain, motor neurons, and bone," concluded Shorter.

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Journal Reference:

  1. Hong Joo Kim, Nam Chul Kim, Yong-Dong Wang, Emily A. Scarborough, Jennifer Moore, Zamia Diaz, Kyle S. MacLea, Brian Freibaum, Songqing Li, Amandine Molliex, Anderson P. Kanagaraj, Robert Carter, Kevin B. Boylan, Aleksandra M. Wojtas, Rosa Rademakers, Jack L. Pinkus, Steven A. Greenberg, John Q. Trojanowski, Bryan J. Traynor, Bradley N. Smith, Simon Topp, Athina-Soragia Gkazi, Jack Miller, Christopher E. Shaw, Michael Kottlors, Janbernd Kirschner, Alan Pestronk, Yun R. Li, Alice Flynn Ford, Aaron D. Gitler, Michael Benatar, Oliver D. King, Virginia E. Kimonis, Eric D. Ross, Conrad C. Weihl, James Shorter, J. Paul Taylor. Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature, 2013; DOI: 10.1038/nature11922

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/05X4esEPrWI/130303154956.htm

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Watch live: SpaceX's Dragon capsule will rendezvous with the ISS today, coverage begins at 3:30AM ET (update: success!)

We told you about it late yesterday, but now it's about time for the livestream of SpaceX's Dragon capsule reaching the International Space Station. If all's going as planned, the craft would've begun some preliminary maneuvers toward the ISS roughly an hour ago. According to the company, astronauts aboard the ISS will attempt to grapple it with a robotic arm at 6:36AM ET. If that's successful, the actual berthing of the capsule is set to begin at 8AM. Don't take our word for it, catch the NASA TV live feed (coverage starts at 3:30AM) at embedded after the break!

Here's to wishing that all continues to go well overall on this resupply effort!

Update 8:21AM: Dragon was captured at 5:31AM and the berthing process is currently taking place. The capsule should be fully in place by roughly 9:40AM! We've also updated the feed past the break, as it was originally pulling from NASA TV's public feed, rather than the ISS feed -- apologies for any inconvenience.

Update 9:03 AM: Dragon was successfully berthed the space station at 8:56AM, ahead of scheduele like much of the event. And with that, NASA has ended coverage of the event. Now those onboard the station will be focused on unloading the supplies it's carrying. Dragon will return to Earth for a splashdown on March 25th. As always, hit the NASA source link for more detailed info. Catch a picture of Dragon attached to the ISS's Harmony node just past the break.

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Source: SpaceX, NASA

Source: http://www.engadget.com/2013/03/03/watch-live-spacexs-dragon-capsule-will-rendezvous-with-the-iss/

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New study reveals how sensitive US East Coast regions may be to ocean acidification

Mar. 1, 2013 ? A continental-scale chemical survey in the waters of the eastern U.S. and Gulf of Mexico is helping researchers determine how distinct bodies of water will resist changes in acidity. The study, which measures varying levels of carbon dioxide (CO2) and other forms of carbon in the ocean, was conducted by scientists from 11 institutions across the U.S. and was published in the journal Limnology and Oceanography.

"Before now, we haven't had a very clear picture of acidification status on the east coast of the U.S.," says Zhaohui 'Aleck' Wang, the study's lead author and a chemical oceanographer at Woods Hole Oceanographic Institution (WHOI). "It's important that we start to understand it, because increase in ocean acidity could deeply affect marine life along the coast and has important implications for people who rely on aquaculture and fisheries both commercially and recreationally."

Coastal ocean acidification, Wang says, can occur when excess carbon dioxide is absorbed by, flushed into or generated in coastal waters, setting off a chain of chemical reactions that lowers the water's pH, making it more acidic. The process disproportionately affects species like oysters, snails, pteropods, and coral, since those organisms cannot effectively form shells in a more acidic environment.

According to the survey, says Wang, different regions of coastal ocean will respond to an influx of CO2 in different ways. "If you put the same amount of CO2 into both the Gulf of Maine and the Gulf of Mexico right now, the ecosystem in the Gulf of Maine would probably feel the effects more dramatically," he says. "Acidity is already relatively high in that region, and the saturation of calcium carbonate -- the mineral that many organisms need to make shells -- is particularly low. It's not a great situation."

Excess CO2 can enter coastal waters from a variety of different sources, Wang says. One large source is carbon dioxide in the atmosphere, which has been steadily increasing in concentration worldwide for the past hundred and fifty years. The higher those levels of atmospheric CO2 rise, more CO2 gas will be absorbed into seawater by contact, says Wang. Another potential culprit, he notes, is nutrient-rich runoff from land. Rainfall and other surface flows can wash fertilizers and other byproducts of human activities into river systems and ground water, and ultimately, into the coastal ocean, delivering an excess of nutrients and often an explosion of biological activity that can lead to decreased oxygen and increased CO2 and acidity.

"This happens regularly in the Gulf of Mexico," says Wang. "The Mississippi River dumps enormous amounts of nitrogen and other nutrients into the Gulf, which spawns large algal blooms that lead to production of large amount of organic matter. In the process of decomposing the organic matter, the microbes consume oxygen in the water and leave carbon dioxide behind, making the water more acidic. If this process happens in the Gulf of Maine, the ecosystem there may be even more vulnerable since the Gulf of Maine is a semi-enclosed system and it may take longer time for low pH, low oxygen water to disperse."

Wang and his colleagues conducted their fieldwork in 2007 aboard the R/V Ronald H. Brown. Starting in the waters off Galveston, Texas, they worked their way around the Louisiana and west Florida coasts, past the Florida Straight, and up the eastern seaboard, collecting samples along nine different transects that ran from the coast to deep ocean off the shelf break, up to 480km (300 miles) offshore.

During the cruise, the researchers measured seawater samples for total dissolved inorganic carbon (DIC), which is made up of a combination of carbonate, bicarbonate, dissolved CO2 and carbonic acid. The team compared this measurement to the water's total alkalinity, a measure of how much base is in a water sample. The ratio of the two is a marker for water's ability to "buffer" or resist changes in acidity. Waters with a high ratio of alkalinity to DIC, Wang says, would be less susceptible to acidification than waters that showed a much lower ratio.

After analyzing their data, Wang and colleagues found that, despite a "dead zone" of low oxygen and high acidity outside the mouth of the Mississippi, the Gulf of Mexico on the whole showed a high ratio of alkalinity to DIC, meaning it would be more resistant to acidification. As the team traveled farther north, however, they saw the ratio steadily decreases north of Georgia. The waters in the Gulf of Maine, Wang says, on average had the lowest alkalinity to DIC ratio of any region along the eastern seaboard, meaning that it would be especially vulnerable to acidification should CO2 levels rise in those waters.

While it's unclear exactly why the ratio of alkalinity to DIC is low in those northern waters, Wang thinks part of the issue may be linked to alkalinity sources to the region. For example, the Labrador Coastal Current brings relatively fresh, low alkalinity water down from the Labrador Sea to the Gulf of Maine and Middle Atlantic Bight.

If this current is the major source of alkalinity to the region, he says, it may mean that the Gulf of Maine's fate could be linked to changes in global climate that, through melting sea ice and glaciers, increase the flow of fresh water to the Gulf of Maine. However, whether this freshening is accompanied by a decreases in seawater alkalinity and "buffer" capacity remains unknown.

Since the waters of the northeast U.S. are already susceptible to rising acidity, Wang says this raises big questions about how species of marine life -- many of which are important to the commercial fishing and shellfish industry there -- will fare in the future. "For example, how are oysters going to do? What about other shellfish? If the food chain changes, how are fish going to be impacted?" Wang asks. "There's a whole range of ecological and sociological questions." There is a great need for need for more robust coastal ocean chemistry monitoring and coastal ocean acidification studies, he adds. A better understanding of the changing chemistry will help fisheries regulators to better manage the stocks.

Also collaborating on the study were Rik Wanninkhof and Tsung-Hung Peng from the National Oceanic and Atmospheric Administration's Atlantic Oceanographic and Meteorological Laboratory, Wei-Jun Cai and Wei-Jen Huang of the University of Georgia, Robert H. Byrne of the University of South Florida, and Xinping Hu of Texas A&M University.

This research was supported by the NOAA Global Carbon Cycle Program.

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The above story is reprinted from materials provided by Woods Hole Oceanographic Institution.

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Journal Reference:

  1. Zhaohui Aleck Wang, Rik Wanninkhof, Wei-Jun Cai, Robert H. Byrne, Xinping Hu, Tsung-Hung Peng, Wei-Jen Huang. The marine inorganic carbon system along the Gulf of Mexico and Atlantic coasts of the United States: Insights from a transregional coastal carbon study. Limnology and Oceanography, 2013; 58 (1): 325 DOI: 10.4319/lo.2013.58.1.0325

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/343bbYlsdBs/130301123042.htm

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শুক্রবার, ১ মার্চ, ২০১৩

Hanwood Holdings are pleased to announce their new movie investment offering - Henry 5

Set 50 years into the future, an over populated Great Britain is totally reliant on France for its electricity. With spiralling costs and with Britain close to bankruptcy this is no longer a tenable position. Only one path is left open... war.

(PRWEB UK) 27 February 2013

Henry 5 is a story of political intrigue and personal ambition that not only reminds us of the Bush / Blair years and the invasion of Iraq, but also sentiments that Shakespeare expressed 400 years ago are as relevant today as they were then, and will be in the future.

Society has not yet descended into a post-apocalyptic maelstrom but the nation is broke and morally in terminal decline. With echoes of Blair and Bush?s invasion of Iraq (which many believe was to do with oil), the King (Henry) decides with his cabinet to ?cook up? a war dossier so that he can ?legally? invade Britain?s closest neighbour - France.

France provides the UK with its electricity and still has wide-open spaces with 100 hectares more land per 1 hectare of England?s soil. Britain is now over populated and breaking at the seams so a fast cabinet decision is pushed through parliament - WAR. Shakespeare provides us with the richness of language to convey this apocalyptic vision perfectly.

England?s only hope of survival is to carry out two tasks in the war manifesto:

1) Take France and control the electricity, gas and coal, which the UK can no longer meet their price demands for.

2) Contain all of the non-British (and the French think non French) within the strict borders of a renamed United Kingdom.

This coup can only be sealed by Henry if he becomes victorious and marries Katherine the daughter of the King and Queen of France. A war cabinet is assembled and the French are denounced as war profiteers ? a decision is passed and war is declared?.

With a planned all-star cast including Ray Winstone (The Sweeny, Snow White & The Huntsman, The Departed, Sweeny Todd), Sir Michael Caine (The Dark Night Rises, Inception, Harry Brown, Batman, The Italian Job), Sir Derek Jacobi (Gladiator, The Kings Speech, My Week With Marilyn), Vinnie Jones (Snatch, Lock Stock & Two Smoking Barrels, X-Men, Gone in Sixty Seconds), Gerard Depardue (Life of Pi, 102 Dalmations, The Man in the Iron Mask, Green Card) & Lord Richard Attenborough (Jurassic Park trilogy, The Great Escape, Hamlet).

If you would like more information about investing in HENRY5, please call Hanwood Holdings Ltd on 0845 862 3090 or email info(at)hanwoodholdings(dot)com

Gary Collins
Hanwood Holdings Ltd
+44 (0)845 8623090
Email Information

Source: http://news.yahoo.com/hanwood-holdings-pleased-announce-movie-investment-offering-henry-081422061.html

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Beyond Kickstarter: Why One Site Shouldn?t Dominate Crowdfunding

Beyond Kickstarter: Why One Site Shouldn’t Dominate Crowdfunding
One site shouldn't dominate crowdfunding. Let's take it niche.

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